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The three "Big" theories in biology that serve as fundamental principles guiding our understanding of the life sciences are Cell Theory, Gene Theory, and Evolution Theory.

Cell Theory posits that all living organisms are composed of cells, the basic unit of life, and that all cells arise from pre-existing cells. This theory emphasizes the importance of cellular organization and function in all living beings.

Gene Theory focuses on the role of genes as the units of heredity that govern the traits and features of organisms. It highlights the mechanisms of genetic inheritance and the way traits are passed from one generation to the next, making it essential for understanding evolution, biology, and genetics.

Evolution Theory explains the diversity of life on Earth and how species adapt over time through processes such as natural selection. This theory provides a framework for understanding how organisms change and persist over generations, linking biology to paleontology and ecology.

Together, these three theories form the foundation of modern biological science, influencing research, education, and our understanding of life processes.